BDBM50173253 2-[1'-cyclooctylmethyl-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]ethyl acetate::CHEMBL373190

SMILES CC(=O)OCCN1C(=O)C2(CCN(CC3CCCCCCC3)CC2)c2ccccc12

InChI Key InChIKey=PJUYFSRWEFJRNZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50173253   

TargetDelta-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173253(2-[1'-cyclooctylmethyl-2-oxospiro[2,3-dihydro-1H-i...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against human opioid receptor delta 1 expressed in HEK293 cells using [3H]DDPDE radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173253(2-[1'-cyclooctylmethyl-2-oxospiro[2,3-dihydro-1H-i...)
Affinity DataIC50: 180nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173253(2-[1'-cyclooctylmethyl-2-oxospiro[2,3-dihydro-1H-i...)
Affinity DataIC50: 1.41E+3nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173253(2-[1'-cyclooctylmethyl-2-oxospiro[2,3-dihydro-1H-i...)
Affinity DataIC50: 2.64E+3nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed