BDBM50173245 1'-cyclooctylmethyl-5-fluoro-1-methylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-2-one::CHEMBL197727

SMILES CN1C(=O)C2(CCN(CC3CCCCCCC3)CC2)c2cc(F)ccc12

InChI Key InChIKey=NRNLUSZSMWQZFV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50173245   

TargetDelta-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173245(1'-cyclooctylmethyl-5-fluoro-1-methylspiro[2,3-dih...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against human opioid receptor delta 1 expressed in HEK293 cells using [3H]DDPDE radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173245(1'-cyclooctylmethyl-5-fluoro-1-methylspiro[2,3-dih...)
Affinity DataIC50: 23nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173245(1'-cyclooctylmethyl-5-fluoro-1-methylspiro[2,3-dih...)
Affinity DataIC50: 1.01E+3nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50173245(1'-cyclooctylmethyl-5-fluoro-1-methylspiro[2,3-dih...)
Affinity DataIC50: 250nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed