BDBM50173225 (S)-2-{4'-[(5-ethyl-4-hydroxy-3-methyl-benzofuran-2-carbonyl)-amino]-biphenyl-4-sulfonylamino}-3-methyl-butyric acid::CHEMBL427366

SMILES CCc1ccc2oc(C(=O)Nc3ccc(cc3)-c3ccc(cc3)S(=O)(=O)N[C@@H](C(C)C)C(O)=O)c(C)c2c1O

InChI Key InChIKey=USIMDPVZFWUXPH-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50173225   

TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173225((S)-2-{4'-[(5-ethyl-4-hydroxy-3-methyl-benzofuran-...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibitory concentration against MMP-14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50173225((S)-2-{4'-[(5-ethyl-4-hydroxy-3-methyl-benzofuran-...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory concentration against Aggrecanase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173225((S)-2-{4'-[(5-ethyl-4-hydroxy-3-methyl-benzofuran-...)
Affinity DataIC50: 458nMAssay Description:Inhibitory concentration against MMP-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173225((S)-2-{4'-[(5-ethyl-4-hydroxy-3-methyl-benzofuran-...)
Affinity DataIC50: 2.34E+4nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173225((S)-2-{4'-[(5-ethyl-4-hydroxy-3-methyl-benzofuran-...)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibitory concentration against MMP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173225((S)-2-{4'-[(5-ethyl-4-hydroxy-3-methyl-benzofuran-...)
Affinity DataIC50: 492nMAssay Description:Inhibitory concentration against MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173225((S)-2-{4'-[(5-ethyl-4-hydroxy-3-methyl-benzofuran-...)
Affinity DataIC50: 94nMAssay Description:Inhibitory concentration against MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173225((S)-2-{4'-[(5-ethyl-4-hydroxy-3-methyl-benzofuran-...)
Affinity DataIC50: 7.10nMAssay Description:Inhibitory concentration against MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173225((S)-2-{4'-[(5-ethyl-4-hydroxy-3-methyl-benzofuran-...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed