BDBM501732 N-Cyclopentyl-3-(5-((7-(2-(dimethylamino)ethoxy)-5-methoxy-9-oxo-9H-xanthen-3-yl)oxy)pyridin-2-yl)propanamide::US11028064, Example 46

SMILES COc1cc(OCCN(C)C)cc2c1oc1cc(Oc3ccc(CCC(=O)NC4CCCC4)nc3)ccc1c2=O

InChI Key InChIKey=ZXZUGAJHYNMGOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501732   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Auckland Uniservices

US Patent
LigandPNGBDBM501732(N-Cyclopentyl-3-(5-((7-(2-(dimethylamino)ethoxy)-5...)
Affinity DataIC50: 100nMAssay Description:IC50 values were determined using the Z′-LYTE activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Auckland Uniservices

US Patent
LigandPNGBDBM501732(N-Cyclopentyl-3-(5-((7-(2-(dimethylamino)ethoxy)-5...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 values were determined using the Z′-LYTE activity assay, with ATP concentration used at Km app for the specific assay (500 μM ATP for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent