BDBM50173168 4-[(S)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxymethyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl]-pyrimidin-2-ylamine::CHEMBL372082

SMILES COc1ccc(COC[C@@H]2CCc3nc(c(-c4ccnc(N)n4)n23)-c2ccc(F)cc2)cc1

InChI Key InChIKey=BKLYUVKUMMLBIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173168   

TargetMitogen-activated protein kinase 10(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50173168(4-[(S)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...)
Affinity DataIC50: 61.2nMAssay Description:Inhibitory activity against c-Jun N-terminal kinase 3 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50173168(4-[(S)-2-(4-Fluoro-phenyl)-5-(4-methoxy-benzyloxym...)
Affinity DataIC50: 295nMAssay Description:Inhibitory activity against p38 at a concentration of 1.0 uM More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed