BDBM50172416 CHEMBL427540::N-[2-(2,5-Diaza-bicyclo[2.2.1]hept-2-yl)-4-methyl-quinolin-6-yl]-2-(4-trifluoromethoxy-phenoxy)-acetamide

SMILES Cc1cc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CC2CC1CN2

InChI Key InChIKey=QJVKSHKJQIYIKU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172416   

TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172416(N-[2-(2,5-Diaza-bicyclo[2.2.1]hept-2-yl)-4-methyl-...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of 15 pM [125I]MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172416(N-[2-(2,5-Diaza-bicyclo[2.2.1]hept-2-yl)-4-methyl-...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH2R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172416(N-[2-(2,5-Diaza-bicyclo[2.2.1]hept-2-yl)-4-methyl-...)
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against 10 nM MCH-induced IP3 accumulation in CHO-K1 cells expressing human MCH1R after incubation with [3H]myo-inositolMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172416(N-[2-(2,5-Diaza-bicyclo[2.2.1]hept-2-yl)-4-methyl-...)
Affinity DataIC50: 9.70nMAssay Description:Displacement of 150p M [125I]MCH from human MCH1R expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed