BDBM50171642 5-(3,3-Dimethyl-butyrylamino)-1-(2-fluoro-benzyl)-1H-indole-2-carboxylic acid (6-chloro-pyridin-3-yl)-amide::CHEMBL196327::ECE Inhibitor, 9

SMILES CC(C)(C)CC(=O)Nc1ccc2n(Cc3ccccc3F)c(cc2c1)C(=O)Nc1ccc(Cl)nc1

InChI Key InChIKey=JHKWHKDEMRPRGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171642   

TargetEndothelin-converting enzyme 1(Rat)
Bayer Healthcare

LigandPNGBDBM50171642(ECE Inhibitor, 9 | CHEMBL196327 | 5-(3,3-Dimethyl-...)
Affinity DataIC50: 220nMAssay Description:Inhibition assay using ECE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2013
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50171642(ECE Inhibitor, 9 | CHEMBL196327 | 5-(3,3-Dimethyl-...)
Affinity DataIC50: 440nMAssay Description:Inhibitory concentration against endothelin converting enzyme 1 using bradykinin-derived substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed