BDBM50171412 5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-phenyl)-[1,2,4]oxadiazole::CHEMBL190274

SMILES FC(F)(F)c1ccc(cc1)-c1noc(n1)-c1sccc1Cl

InChI Key InChIKey=PDJHJNIKXHBBMQ-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50171412   

TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50:  1.21E+3nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50: >4.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50:  3.34E+3nMAssay Description:Caspase-3 activation activity tested in ZR-75-1 cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50:  440nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in LnCap cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50:  760nMAssay Description:Caspase-3 activation activity tested in HT-29 cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171412(5-(3-Chloro-thiophen-2-yl)-3-(4-trifluoromethyl-ph...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in P338 cancer cells done for 24 or 48 hr at 37 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed