BDBM50170939 CHEMBL3806052

SMILES N[C@H]1C[C@H](CO[C@@H]1c1cc(F)ccc1F)N1Cc2nn3nccnc3c2C1

InChI Key InChIKey=LRWYEPLNZNSEKG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50170939   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170939(CHEMBL3806052)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170939(CHEMBL3806052)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170939(CHEMBL3806052)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170939(CHEMBL3806052)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170939(CHEMBL3806052)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170939(CHEMBL3806052)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170939(CHEMBL3806052)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2017
Entry Details Article
PubMed