BDBM50169701 (3-Chloro-4-fluoro-phenyl)-(1,3,8a,9-tetraaza-fluoren-4-yl)-amine::CHEMBL181275

SMILES Fc1ccc(Nc2ncnc3nn4ccccc4c23)cc1Cl

InChI Key InChIKey=KHIJZOQIPUVEBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169701   

TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169701((3-Chloro-4-fluoro-phenyl)-(1,3,8a,9-tetraaza-fluo...)
Affinity DataIC50: 200nMpH: 7.5Assay Description:Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169701((3-Chloro-4-fluoro-phenyl)-(1,3,8a,9-tetraaza-fluo...)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed