BDBM50169697 CHEMBL182254::[3-Chloro-4-(3-fluoro-benzyloxy)-phenyl]-(1,3,8a,9-tetraaza-fluoren-4-yl)-amine

SMILES Fc1cccc(COc2ccc(Nc3ncnc4nn5ccccc5c34)cc2Cl)c1

InChI Key InChIKey=XYKNCRFMAKMJKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169697   

TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169697([3-Chloro-4-(3-fluoro-benzyloxy)-phenyl]-(1,3,8a,9...)
Affinity DataIC50: 32nMpH: 7.5Assay Description:Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169697([3-Chloro-4-(3-fluoro-benzyloxy)-phenyl]-(1,3,8a,9...)
Affinity DataIC50: 63nMpH: 7.5Assay Description:Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed