BDBM50169054 CHEMBL3805390

SMILES COCC(C1CC1)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12

InChI Key InChIKey=ZBPMJTCUOXGGGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50169054   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169054(CHEMBL3805390)
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of MALT1 (unknown origin) expressed in human Jurkat Clone K22 29Q_H23 cells assessed as IL2 production preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50169054(CHEMBL3805390)
Affinity DataIC50: 0.00600nMAssay Description:Inhibition of MALT1 C domain (329 to 824 residues) (unknown origin) using Ac-Trp-Leu-Arg-Ser-Arg-Cys(PT14)-NH2 as substrate preincubated for 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2017
Entry Details Article
PubMed