BDBM50169044 (-)-ibuprofen::(2R)-2-(4-isobutylphenyl)propanoic acid::(2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid::(R)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::CHEMBL427526::IBUPROFEN LYSINE::levibuprofen

SMILES CC(C)Cc1ccc(cc1)[C@@H](C)C(O)=O

InChI Key InChIKey=HEFNNWSXXWATRW-UHFFFAOYSA-N

Data  4 IC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169044   

TargetInterleukin-8(Human)
Grupo Uriach

Curated by ChEMBL
LigandPNGBDBM50169044((2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid | ...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50169044((2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid | ...)
Affinity DataIC50: 3.89E+5nMAssay Description:Inhibition of rat ASIC3 receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.4-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50169044((2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid | ...)
Affinity DataIC50: 2.88E+5nMAssay Description:Inhibition of rat ASIC1a receptor expressed in xenopus lavies oocytes assessed as inhibition of pH 6.7-gated currents by two electrode voltage clampMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-X-C chemokine receptor type 1/2(Human)
Domp£

Curated by ChEMBL
LigandPNGBDBM50169044((2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid | ...)
Affinity DataIC50: 110nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed