BDBM50168371 6-(3-Hydroxy-phenyl)-naphthalen-2-ol::6-(3-hydroxyphenyl)-2-naphthol::6-(3-hydroxyphenyl)naphthalen-2-ol::CHEMBL195217

SMILES Oc1cccc(c1)-c1ccc2cc(O)ccc2c1

InChI Key InChIKey=VHWBXEUHUQDHDH-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50168371   

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 5.64E+3nMAssay Description:Displacement of [3H]E2 from human placental 17beta-HSD2 after 10 mins by fluid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 5.64E+3nMAssay Description:Inhibition of human placental 17beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 116nMAssay Description:Inhibition of human placental 17beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of human CYP2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 116nMAssay Description:Inhibition of human placental 17beta-HSD1 assessed as conversion of [3H]estrone to [3H]17beta-estradiolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 5.64E+3nMAssay Description:Inhibition of [3H]E2 binding to human placental 17beta-HSD2 after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 5.64E+3nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as conversion of [3H]17beta-estradiol to [3H]estroneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to human estrogen receptor beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 230nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 116nMAssay Description:Displacement of [3H]E1 from human placental 17beta-HSD1 after 10 mins by fluid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 229nMAssay Description:Displacement of [3H]E1 from 17beta-HSD1 in human T47D cells after 10 mins by fluid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50: 116nMAssay Description:Inhibition of [3H]E1 binding to human placental 17beta-HSD1 after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed