BDBM50168134 CHEMBL3741532

SMILES CCn1c(CNc2ccc(cc2F)C(N)=N)nc2cc(ccc12)C(=O)N(CCC(O)=O)c1cc(C)ccn1

InChI Key InChIKey=XKFUKCINIVXNPZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50168134   

TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50168134(CHEMBL3741532)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured within 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50168134(CHEMBL3741532)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured within 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50168134(CHEMBL3741532)
Affinity DataIC50: 19nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed