BDBM50168129 CHEMBL3799876

SMILES CCn1c(CNc2ccc(cc2F)C(N)=N)nc2cc(ccc12)C(=O)N(CCC(O)=O)c1c(C)cccc1C

InChI Key InChIKey=JBYKSDBYLCMNSX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168129   

TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50168129(CHEMBL3799876)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured within 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50168129(CHEMBL3799876)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured within 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2017
Entry Details Article
PubMed