BDBM50167514 CHEMBL370463::[4-(3-Aminomethyl-phenyl)-piperidin-1-yl]-(1-butyl-7-methyl-1H-indol-3-yl)-methanone; TFA

SMILES CCCCn1cc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c2cccc(C)c12

InChI Key InChIKey=AOXSCJZNRWXTAM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50167514   

TargetTryptase beta-2(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167514([4-(3-Aminomethyl-phenyl)-piperidin-1-yl]-(1-butyl...)
Affinity DataIC50: 68nMAssay Description:Inhibition concentration against beta tryptase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167514([4-(3-Aminomethyl-phenyl)-piperidin-1-yl]-(1-butyl...)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibitory concentration against alpha tryptase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50167514([4-(3-Aminomethyl-phenyl)-piperidin-1-yl]-(1-butyl...)
Affinity DataKi:  68nMAssay Description:In vitro inhibitory activity against tryptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed