BDBM50167307 1-Benzo[b]thiophen-2-ylmethyl-5-iodo-1H-indole-2,3-dione::CHEMBL190743::acs.jmedchem.1c00409_ST.233::med.21724, Compound 106

SMILES Ic1ccc2N(Cc3cc4ccccc4s3)C(=O)C(=O)c2c1

InChI Key InChIKey=MAYSJMBSILUGEG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50167307   

TargetReplicase polyprotein 1a(SARS-CoV)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167307(1-Benzo[b]thiophen-2-ylmethyl-5-iodo-1H-indole-2,3...)
Affinity DataIC50: 950nMAssay Description:In vitro inhibitory concentration against SARS coronavirus main protease (SARS CoV 3C-like protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50167307(1-Benzo[b]thiophen-2-ylmethyl-5-iodo-1H-indole-2,3...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration against Chymotrypsin (serine protease)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Bonn

LigandPNGBDBM50167307(1-Benzo[b]thiophen-2-ylmethyl-5-iodo-1H-indole-2,3...)
Affinity DataIC50: 950nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Bonn

LigandPNGBDBM50167307(1-Benzo[b]thiophen-2-ylmethyl-5-iodo-1H-indole-2,3...)
Affinity DataIC50: 950nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed