BDBM50166450 (R)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-amino-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)pyrimidine-2,4(1H,3H)-dione::(R)-3-(2-amino-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)pyrimidine-2,4(1H,3H)-dione::3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-fluoro-3-methoxy-phenyl)-1-(2-fluoro-6-trifluoromethyl-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL434936
SMILES COc1cccc(c1F)-c1cn(Cc2c(F)cccc2C(F)(F)F)c(=O)n(C[C@H](N)c2ccccc2)c1=O
InChI Key InChIKey=JZIURJIEJBKSKI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50166450
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant CYP3A4 by microtiter plate-based fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [125I]Pro-N-Et-GnRH from human cloned GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor (GNRHR) using GnRH peptide as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Binding affinity to human GnRHRMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Binding affinity at human GnRH receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from human GnRH receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair