BDBM50166318 (S)-1-[(2S,4S)-4-(3-Chloro-4-cyano-phenylamino)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile::CHEMBL194717

SMILES Clc1cc(N[C@@H]2CN[C@@H](C2)C(=O)N2CCC[C@H]2C#N)ccc1C#N

InChI Key InChIKey=IBCANTWOKYWQJY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50166318   

TargetDipeptidyl peptidase 4(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50166318((S)-1-[(2S,4S)-4-(3-Chloro-4-cyano-phenylamino)-py...)
Affinity DataIC50: 0.150nMAssay Description:Inhibitory concentration against rat dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50166318((S)-1-[(2S,4S)-4-(3-Chloro-4-cyano-phenylamino)-py...)
Affinity DataIC50: 0.130nMAssay Description:Inhibitory concentration against human dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50166318((S)-1-[(2S,4S)-4-(3-Chloro-4-cyano-phenylamino)-py...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50166318((S)-1-[(2S,4S)-4-(3-Chloro-4-cyano-phenylamino)-py...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of DPP4 in rat plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed