BDBM50165301 9-(2-Isopropoxy-ethyl)-8-(3,4,5-trimethoxy-phenylsulfanyl)-9H-purin-6-ylamine::CHEMBL191668

SMILES COc1cc(Sc2nc3c(N)ncnc3n2CCOC(C)C)cc(OC)c1OC

InChI Key InChIKey=KEAAYBPDOZWODP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165301   

TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165301(9-(2-Isopropoxy-ethyl)-8-(3,4,5-trimethoxy-phenyls...)
Affinity DataEC50:  3.40E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165301(9-(2-Isopropoxy-ethyl)-8-(3,4,5-trimethoxy-phenyls...)
Affinity DataIC50: 6.53E+4nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed