BDBM50165280 9-Pent-4-ynyl-8-(3,4,5-trimethoxy-benzenesulfonyl)-9H-purin-6-ylamine::CHEMBL193310

SMILES COc1cc(cc(OC)c1OC)S(=O)(=O)c1nc2c(N)ncnc2n1CCCC#C

InChI Key InChIKey=QCCUXARSTIGMJB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165280   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165280(9-Pent-4-ynyl-8-(3,4,5-trimethoxy-benzenesulfonyl)...)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165280(9-Pent-4-ynyl-8-(3,4,5-trimethoxy-benzenesulfonyl)...)
Affinity DataEC50: >5.00E+4nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed