BDBM50164649 CHEMBL3799897

SMILES ONC(=O)c1cccc(NCc2ccccc2)c1

InChI Key InChIKey=SQFOJBYAJUPZOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164649   

TargetHistone deacetylase 8(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164649(CHEMBL3799897)
Affinity DataIC50: 143nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164649(CHEMBL3799897)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2017
Entry Details Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164649(CHEMBL3799897)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2019
Entry Details Article
PubMed