BDBM50164212 2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-2-methyl-butyric acid::CHEMBL364774

SMILES CCCc1cc2c(noc2c(CCC)c1OC(C)(CC)C(O)=O)C(F)(F)F

InChI Key InChIKey=JJPUBDOPZUUOMU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164212   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164212(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataEC50:  750nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164212(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164212(2-(5,7-Dipropyl-3-trifluoromethyl-benzo[d]isoxazol...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alpha bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed