BDBM50163445 (2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol::CHEMBL179409::L-altro-1-Deoxynojirimycin

SMILES OC[C@@H]1NC[C@H](O)[C@@H](O)[C@H]1O

InChI Key InChIKey=LXBIFEVIBLOUGU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50163445   

TargetSucrase-isomaltase, intestinal(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50163445((2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of sucrase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50163445((2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GCS by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLactase/phlorizin hydrolase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50163445((2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of lactase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50163445((2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50163445((2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetGlycogen debranching enzyme(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50163445((2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of glycogen glycogen de-branching enzyme by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMaltase-glucoamylase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50163445((2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of maltase by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPutative alpha-glucosidase(Rice)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50163445((2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibitory concentration against rice alpha-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed