BDBM50163144 CHEMBL414778::H-Tyr-Val-Nle-Gly-His-D-Nal(2'')-Arg-D-Phe-Asp-Arg-Phe-Gly-NH2

SMILES CCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)ON

InChI Key InChIKey=OHFMRHZLQMSCRN-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50163144   

TargetMelanocortin receptor 3(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50163144(H-Tyr-Val-Nle-Gly-His-D-Nal(2'')-Arg-D-Phe-Asp-Arg...)
Affinity DataIC50: 6nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 3 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50163144(H-Tyr-Val-Nle-Gly-His-D-Nal(2'')-Arg-D-Phe-Asp-Arg...)
Affinity DataEC50:  1.5nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 1 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50163144(H-Tyr-Val-Nle-Gly-His-D-Nal(2'')-Arg-D-Phe-Asp-Arg...)
Affinity DataEC50:  490nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 5 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50163144(H-Tyr-Val-Nle-Gly-His-D-Nal(2'')-Arg-D-Phe-Asp-Arg...)
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 4 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50163144(H-Tyr-Val-Nle-Gly-His-D-Nal(2'')-Arg-D-Phe-Asp-Arg...)
Affinity DataEC50:  951nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 3 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50163144(H-Tyr-Val-Nle-Gly-His-D-Nal(2'')-Arg-D-Phe-Asp-Arg...)
Affinity DataIC50: 20nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 4 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50163144(H-Tyr-Val-Nle-Gly-His-D-Nal(2'')-Arg-D-Phe-Asp-Arg...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50163144(H-Tyr-Val-Nle-Gly-His-D-Nal(2'')-Arg-D-Phe-Asp-Arg...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 5 receptor expressed in HEK293 cells; N = 4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed