BDBM50162967 CHEMBL3792850

SMILES O=C(Nc1ccc(CN2CCN(CC2)c2ccccc2)cc1)c1n[nH]c2ccccc12

InChI Key InChIKey=QHWYQHKGOYXAON-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50162967   

TargetHigh affinity nerve growth factor receptor(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50162967(CHEMBL3792850)
Affinity DataIC50: 137nMAssay Description:Inhibition of human N-terminal GST-tagged TRKA cytoplasmic domain (436 to 790 residues) expressed in baculovirus expression system using fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50162967(CHEMBL3792850)
Affinity DataIC50: 410nMAssay Description:Inhibition of human N-terminal GST-tagged HGK catalytic domain (1 to 328 residues) expressed in baculovirus expression system using fluorescence labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50162967(CHEMBL3792850)
Affinity DataIC50: 9nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus expression system using fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50162967(CHEMBL3792850)
Affinity DataIC50: 10nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus expression system using 5-FAM-peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50162967(CHEMBL3792850)
Affinity DataIC50: 10nMAssay Description:Inhibition of wild type FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed