BDBM50162776 3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naphthalen-2-yloxymethyl]-benzoic acid::CHEMBL426789

SMILES CC(C(c1ccc2cc(OCc3cccc(c3)C(O)=O)ccc2c1)n1ccnc1)N(C)C

InChI Key InChIKey=LUDUPPNOCMHNSY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50162776   

TargetCytochrome P450 26A1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162776(3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naph...)
Affinity DataIC50: 3.5nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162776(3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naph...)
Affinity DataIC50: 3.79E+3nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162776(3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naph...)
Affinity DataIC50: 3.5nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162776(3-[6-(2-Dimethylamino-1-imidazol-1-yl-propyl)-naph...)
Affinity DataIC50: 3.79E+3nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed