BDBM50162284 CHEMBL3793530

SMILES COc1ccc2c(c1)occ(Cc1c[nH]cn1)c2=O

InChI Key InChIKey=INEMNHDNMHFZNK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50162284   

TargetCytochrome P450 11B1, mitochondrial(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50: 109nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2017
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2017
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]-androstenedione as substrate for 3 hrs measured as formation of [3]H2O in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2017
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-transfected with rat NADPH-P450 reductase using progesterone as substrate for 30 mins meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2017
Entry Details Article
PubMed