BDBM50162166 1-[2-Chloro-4-(6,7-dimethoxy-quinolin-4-yloxy)-phenyl]-3-(2,4-difluoro-phenyl)-urea::CHEMBL279351

SMILES COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(F)cc4F)c(Cl)c3)c2cc1OC

InChI Key InChIKey=XPTCORXIXMSWEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162166   

TargetPlatelet-derived growth factor receptor alpha(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50162166(1-[2-Chloro-4-(6,7-dimethoxy-quinolin-4-yloxy)-phe...)
Affinity DataIC50: 3nMAssay Description:Inhibition of platelet-derived growth factor receptor alpha in cell-intact assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50162166(1-[2-Chloro-4-(6,7-dimethoxy-quinolin-4-yloxy)-phe...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed