BDBM50161832 CHEMBL3792517

SMILES CCCN(CCC)c1ccc(Cl)c2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12

InChI Key InChIKey=UGGBJUVBTGDGAH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50161832   

TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50161832(CHEMBL3792517)
Affinity DataIC50: 88nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-stimulated cAMP accumulation after 4 hrs by steady-gl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50161832(CHEMBL3792517)
Affinity DataIC50: 9.5nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50161832(CHEMBL3792517)
Affinity DataIC50: 9.5nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes preincubated for 1 hr followed by [125I]-CRF addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed