BDBM50159492 CHEMBL3786336

SMILES CC(C)OC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1ccoc1

InChI Key InChIKey=CVPPUYGSPNIDQH-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50159492   

TargetCytochrome P450 3A4(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159492(CHEMBL3786336)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) expressed in insect cell microsomes using dibenzylfluorescein substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159492(CHEMBL3786336)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using DBF as substrate preincubated for 5 mins followed by substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAdenosine receptor A2b(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159492(CHEMBL3786336)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A2B receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159492(CHEMBL3786336)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DPCPX from human recombinant A2B receptor expressed in human HEK293 cell membranes incubated for 30 mins by radioligand binding c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159492(CHEMBL3786336)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DPCPX from human recombinant A2B receptor expressed in human HEK293 cell membranes incubated for 30 mins by radioligand binding c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159492(CHEMBL3786336)
Affinity DataKi:  11nMAssay Description:Displacement [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159492(CHEMBL3786336)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DPCPX from human A2BAR expressed in HEK293 cell membrane assessed as inhibition constant incubated for 30 mins by competitive bin...More data for this Ligand-Target Pair
In DepthDetails
PubMed