BDBM50159366 (2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyloxymethyl)-pyrrolidine-1-carboxylic acid 2,3-dihydro-benzo[1,4]dioxin-5-yl ester::CHEMBL191879

SMILES CC(=O)S[C@@H]1C[C@@H](COCc2cc(F)c(F)cc2F)N(C1)C(=O)Oc1cccc2OCCOc12

InChI Key InChIKey=VILIDDZBEXSSLV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159366   

TargetNeprilysin(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159366((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against NeprilysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159366((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against human angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159366((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...)
Affinity DataIC50: 76.5nMAssay Description:Inhibitory concentration against human ECE-1 expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159366((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...)
Affinity DataIC50: 6.90nMAssay Description:Inhibitory concentration against human ECE-1 by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed