BDBM50159031 4-Benzyl-1-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-piperidine::CHEMBL180119

SMILES COc1cccc2CC(CN3CCC(Cc4ccccc4)CC3)CCc12

InChI Key InChIKey=AEUPQCCDJKDASR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159031   

TargetSigma non-opioid intracellular receptor 1(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50159031(4-Benzyl-1-(5-methoxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  9.90nMAssay Description:Inhibitory constant against sigma receptor type 2 using 3 nM [3H]ditolylguanidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50159031(4-Benzyl-1-(5-methoxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi:  83.4nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50159031(4-Benzyl-1-(5-methoxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory constant was determined against 5-hydroxytryptamine 1A receptor using 1.2 nM [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50159031(4-Benzyl-1-(5-methoxy-1,2,3,4-tetrahydro-naphthale...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory constant against dopamine D2 receptor using 0.2 nM [3H]-spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed