BDBM50158919 3-Thiophen-2-yl-pyridine::CHEMBL179618::US8609708, 33

SMILES c1csc(c1)-c1cccnc1

InChI Key InChIKey=ZHBLIWDUZHFSJW-UHFFFAOYSA-N

Data  1 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50158919   

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataIC50: 7.80E+3nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataIC50: 3.05E+3nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataIC50: 7.80E+3nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibitory concentration value against human cytochrome P-450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataIC50: 7.08E+4nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataIC50: 9.92E+4nMAssay Description:Inhibitory concentration against human cytochrome P-450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Human Biomolecular Research Institute

US Patent
LigandPNGBDBM50158919(US8609708, 33 | CHEMBL179618 | 3-Thiophen-2-yl-pyr...)
Affinity DataKi:  1.20E+3nMAssay Description:Effect on coumarin 7-hydroxylation by human Cytochrome P-450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed