BDBM50157739 CHEMBL426564::N'-(2-oxo-1-(2-oxo-2-(phenylamino)ethyl)indolin-3-ylidene)isonicotinohydrazide

SMILES O=C(CN1C(=O)C(=NNC(=O)c2ccncc2)c2ccccc12)Nc1ccccc1

InChI Key InChIKey=ZPDPWQKTWXAOSS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157739   

TargetCysteine protease(Leishmania donovani)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50157739(N'-(2-oxo-1-(2-oxo-2-(phenylamino)ethyl)indolin-3-...)
Affinity DataIC50: 6.26E+4nMAssay Description:Inhibition of Leishmania donovani cysteine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50157739(N'-(2-oxo-1-(2-oxo-2-(phenylamino)ethyl)indolin-3-...)
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetCysteine protease falcipain-3 [5-492](malaria parasite P. falciparum)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50157739(N'-(2-oxo-1-(2-oxo-2-(phenylamino)ethyl)indolin-3-...)
Affinity DataIC50: 6.22E+4nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed