BDBM50157722 CHEMBL3787323

SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc(CCC(O)=O)cc1

InChI Key InChIKey=HOUMKQOYHWVXDO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157722   

TargetCytochrome P450 26B1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157722(CHEMBL3787323)
Affinity DataIC50: 680nMAssay Description:Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157722(CHEMBL3787323)
Affinity DataIC50: 270nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The University of Montana

Curated by ChEMBL
LigandPNGBDBM50157722(CHEMBL3787323)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed