BDBM50157586 (S)-tert-butyl 2-((R)-2-(3-benzyl-3-((2R,3R)-3-(tert-butoxycarbonyl)-2-hydroxy-4-phenylbutyl)ureido)-4-methylpentanamido)-4-methylpentanoate::CHEMBL224749

SMILES CC(C)C[C@@H](NC(=O)N(C[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)OC(C)(C)C

InChI Key InChIKey=CSLJDRXHEMEGGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157586   

LigandPNGBDBM50157586((S)-tert-butyl 2-((R)-2-(3-benzyl-3-((2R,3R)-3-(te...)
Affinity DataIC50: 600nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP after 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50157586((S)-tert-butyl 2-((R)-2-(3-benzyl-3-((2R,3R)-3-(te...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed