BDBM50157586 (S)-tert-butyl 2-((R)-2-(3-benzyl-3-((2R,3R)-3-(tert-butoxycarbonyl)-2-hydroxy-4-phenylbutyl)ureido)-4-methylpentanamido)-4-methylpentanoate::CHEMBL224749
SMILES CC(C)C[C@@H](NC(=O)N(C[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)OC(C)(C)C
InChI Key InChIKey=CSLJDRXHEMEGGA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50157586
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP after 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP after 24 hrs by ELISAMore data for this Ligand-Target Pair