BDBM50157581 (S)-methyl 2-((S)-2-(3-benzyl-3-((2R,3R)-3-(tert-butoxycarbonyl)-2-hydroxy-4-phenylbutyl)ureido)-4-methylpentanamido)-3-methylbutanoate::CHEMBL222915

SMILES COC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)N(C[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1)C(C)C

InChI Key InChIKey=DINAVFJXFRFCRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157581   

LigandPNGBDBM50157581((S)-methyl 2-((S)-2-(3-benzyl-3-((2R,3R)-3-(tert-b...)
Affinity DataIC50: 10nMAssay Description:Inhibition of gamma secretase isolated from HeLa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50157581((S)-methyl 2-((S)-2-(3-benzyl-3-((2R,3R)-3-(tert-b...)
Affinity DataIC50: 400nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed