BDBM50157579 (R)-tert-butyl 2-((S)-2-(3-benzyl-3-((2R,3S)-3-(tert-butoxycarbonyl)-2-hydroxy-4-phenylbutyl)ureido)-4-methylpentanamido)-4-methylpentanoate::CHEMBL389952

SMILES CC(C)C[C@H](NC(=O)N(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1)C(=O)N[C@H](CC(C)C)C(=O)OC(C)(C)C

InChI Key InChIKey=CSLJDRXHEMEGGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157579   

LigandPNGBDBM50157579((R)-tert-butyl 2-((S)-2-(3-benzyl-3-((2R,3S)-3-(te...)
Affinity DataIC50: 400nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP after 4 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50157579((R)-tert-butyl 2-((S)-2-(3-benzyl-3-((2R,3S)-3-(te...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed