BDBM50157576 (R)-methyl 2-((R)-2-(3-((2R,3R)-3-(tert-butoxycarbonyl)-2-hydroxy-4-phenylbutyl)-3-isopropylureido)-4-methylpentanamido)-3-methylbutanoate::CHEMBL83509

SMILES COC(=O)[C@H](NC(=O)[C@@H](CC(C)C)NC(=O)N(C[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)C)C(C)C

InChI Key InChIKey=WNXCQTNKLOEILK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157576   

LigandPNGBDBM50157576((R)-methyl 2-((R)-2-(3-((2R,3R)-3-(tert-butoxycarb...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of gamma secretase isolated from HeLa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50157576((R)-methyl 2-((R)-2-(3-((2R,3R)-3-(tert-butoxycarb...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of gamma secretase in CHO cells expressing human APP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed