BDBM50157273 (R)-1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-pyridin-2-yl}-pyrrolidine-2-carboxylic acid::CHEMBL183523

SMILES Cn1cncc1C(OCc1ccc(C#N)c(n1)N1CCC[C@@H]1C(O)=O)c1ccc(C#N)c(c1)-c1ccccc1C(F)(F)F

InChI Key InChIKey=OMLUKPKZEVJCTG-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157273   

LigandPNGBDBM50157273((R)-1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-bip...)
Affinity DataIC50: 680nMAssay Description:Inhibition of Bovine geranylgeranyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157273((R)-1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-bip...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157273((R)-1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-bip...)
Affinity DataEC50:  210nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed