BDBM50157258 CHEMBL361353::N-(1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-pyridin-2-yl}-pyrrolidin-3-yl)-acetamide

SMILES CC(=O)NC1CCN(C1)c1nc(COC(c2cncn2C)c2ccc(C#N)c(c2)-c2ccccc2C(F)(F)F)ccc1C#N

InChI Key InChIKey=BNHGUWSAFIQWGI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157258   

LigandPNGBDBM50157258(N-(1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-biph...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157258(N-(1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-biph...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Bovine geranylgeranyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157258(N-(1-{3-Cyano-6-[(6-cyano-2''-trifluoromethyl-biph...)
Affinity DataEC50:  330nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed