BDBM50157246 6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-4-hydroxymethyl-3,4,5,6-tetrahydro-2H-[1,2'']bipyridinyl-3''-carbonitrile::CHEMBL183356

SMILES Cn1cncc1C(OCc1ccc(C#N)c(n1)N1CCC(CO)CC1)c1ccc(C#N)c(c1)-c1ccccc1C(F)(F)F

InChI Key InChIKey=HOXZKLJQMVOWCB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157246   

LigandPNGBDBM50157246(6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157246(6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Bovine geranylgeranyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157246(6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(...)
Affinity DataEC50:  11nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed