BDBM50157236 6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-2-(3-fluoro-benzylamino)-nicotinonitrile::CHEMBL182180

SMILES Cn1cncc1C(OCc1ccc(C#N)c(NCc2cccc(F)c2)n1)c1ccc(C#N)c(c1)-c1ccccc1C(F)(F)F

InChI Key InChIKey=JGQUEDHUYFPAJX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157236   

LigandPNGBDBM50157236(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 750nMAssay Description:Inhibition of Bovine geranylgeranyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157236(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157236(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed