BDBM50156923 (1R)-3-alpha-(4-methylphenyl)tropane-2-alpha-carboxylic acid::CHEMBL221993

SMILES COC(=O)[C@H]1[C@H]2CCC(C[C@H]1c1ccc(C)cc1)N2C

InChI Key InChIKey=MMKZDDDDODERSJ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156923   

TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156923((1R)-3-alpha-(4-methylphenyl)tropane-2-alpha-carbo...)
Affinity DataIC50: 3.85E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156923((1R)-3-alpha-(4-methylphenyl)tropane-2-alpha-carbo...)
Affinity DataIC50: 23.4nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156923((1R)-3-alpha-(4-methylphenyl)tropane-2-alpha-carbo...)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156923((1R)-3-alpha-(4-methylphenyl)tropane-2-alpha-carbo...)
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed