BDBM50156921 (1R)-3-alpha-(4-chlorophenyl)tropane-2-alpha-carboxylic acid::CHEMBL374712

SMILES COC(=O)[C@H]1[C@H]2CCC(C[C@H]1c1ccc(Cl)cc1)N2C

InChI Key InChIKey=ZEOHVQFWFVMPGM-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50156921   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156921((1R)-3-alpha-(4-chlorophenyl)tropane-2-alpha-carbo...)
Affinity DataIC50: 11.7nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156921((1R)-3-alpha-(4-chlorophenyl)tropane-2-alpha-carbo...)
Affinity DataIC50: 559nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156921((1R)-3-alpha-(4-chlorophenyl)tropane-2-alpha-carbo...)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156921((1R)-3-alpha-(4-chlorophenyl)tropane-2-alpha-carbo...)
Affinity DataKi:  280nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156921((1R)-3-alpha-(4-chlorophenyl)tropane-2-alpha-carbo...)
Affinity DataKi:  441nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed