BDBM50156919 (2R,3S)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate::(2S,3R)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate::CHEMBL373385

SMILES COC(=O)[C@@H]1C2CCC(C[C@H]1c1ccc(C)cc1)N2C

InChI Key InChIKey=MMKZDDDDODERSJ-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50156919   

TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156919((2S,3R)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataIC50: 270nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156919((2S,3R)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataIC50: 4.25E+3nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156919((2S,3R)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataIC50: 10.2nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156919((2S,3R)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50156919((2S,3R)-methyl 8-methyl-3-p-tolyl-8-aza-bicyclo[3....)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed