BDBM50156872 2-methoxy-5-[4-(1-thiophen-2-ylmethyl-1H-indol-3-yl)-piperidin-1-ylmethyl]benzoic acid::CHEMBL376202

SMILES COc1ccc(CN2CCC(CC2)c2cn(Cc3cccs3)c3ccccc23)cc1C(O)=O

InChI Key InChIKey=ZERWJGDOIKPLKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156872   

TargetHistamine H2 receptor(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50156872(2-methoxy-5-[4-(1-thiophen-2-ylmethyl-1H-indol-3-y...)
Affinity DataIC50: 3.20E+3nMAssay Description:Displacement of [3H]ketanserin from histamine H2 receptor in human cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50156872(2-methoxy-5-[4-(1-thiophen-2-ylmethyl-1H-indol-3-y...)
Affinity DataIC50: 125nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed