BDBM50156870 2-(2-{4-[1-(2-[1,3]dioxolan-2-yl-ethyl)-1H-indol-3-yl]piperidin-1-yl}ethoxy)benzoic acid::CHEMBL374869

SMILES OC(=O)c1ccccc1OCCN1CCC(CC1)c1cn(CCC2OCCO2)c2ccccc12

InChI Key InChIKey=ZUAMSTWVTDGQIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156870   

TargetHistamine H1 receptor(Guinea pig)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50156870(2-(2-{4-[1-(2-[1,3]dioxolan-2-yl-ethyl)-1H-indol-3...)
Affinity DataIC50: 354nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50156870(2-(2-{4-[1-(2-[1,3]dioxolan-2-yl-ethyl)-1H-indol-3...)
Affinity DataIC50: 4.52E+3nMAssay Description:Displacement of [3H]ketanserin from histamine H2 receptor in human cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed